Reaction: Roflumilast to 1 product

N-oxidationMajor circulating metaboliteMetabolism of Roflumilast

Roflumilast is converted to Roflumilast N-oxide by Cytochrome P450 3A4 and Cytochrome P450 1A2.

Direction
Activity
active

What you can answer from here — as of August 03, 2022

2EnzymesEach linked to its target card
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1ReferenceThe literature this reaction is curated from
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Which other drugs are metabolised by Cytochrome P450 3A4 and Cytochrome P450 1A2, and which of those pairings are clinically significant?

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