Reaction: Odanacatib to 1 product

Reaction
Odanacatib
DB06670
M8 (Odanacatib)
DBMET01472
Reaction type
hydroxylation
Direction
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
active
References
  1. Kassahun K, McIntosh I, Koeplinger K, Sun L, Talaty JE, Miller DL, Dixon R, Zajic S, Stoch SA: Disposition and metabolism of the cathepsin K inhibitor odanacatib in humans. Drug Metab Dispos. 2014 May;42(5):818-27. doi: 10.1124/dmd.113.056580. Epub 2014 Feb 19. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 3A4Not AvailableNot Availableimplied
Cytochrome P450 2C8Not AvailableNot Availableimplied