Reaction: Topiroxostat to 1 product
- Reaction
- Reaction type
- 2-hydroxylation
- Direction
- Major circulating metabolite?
- No
- Spontaneous?
- No
- Activity
- active
- References
- Matsumoto K, Okamoto K, Ashizawa N, Nishino T: FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase. J Pharmacol Exp Ther. 2011 Jan;336(1):95-103. doi: 10.1124/jpet.110.174540. Epub 2010 Oct 15. [Article]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Xanthine dehydrogenase/oxidase Not Available Not Available confirmed