Reaction: Zafirlukast to 1 product

Aliphatic hydroxylationMetabolism of Zafirlukast

Zafirlukast is converted to 3-hydroxycyclopentyl N-[3-({2-methoxy-4-[(2-methylbenzenesulfonyl)carbamoyl]phenyl}methyl)-1-methylindol-5-yl]carbamate by Cytochrome P450 2C9 and Cytochrome P450 3A4.

Direction

What you can answer from here — as of October 27, 2017

2EnzymesEach linked to its target card
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1ReferenceThe literature this reaction is curated from
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Which other drugs are metabolised by Cytochrome P450 2C9 and Cytochrome P450 3A4, and which of those pairings are clinically significant?

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