Reaction: Apalutamide to 1 product

N-demethylationMajor circulating metaboliteMetabolism of Apalutamide

Apalutamide is converted to N-desmethyl apalutamide by Cytochrome P450 2C8 and Cytochrome P450 3A4.

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active

What you can answer from here — as of February 15, 2018

2EnzymesEach linked to its target card
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1ReferenceThe literature this reaction is curated from
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Which other drugs are metabolised by Cytochrome P450 2C8 and Cytochrome P450 3A4, and which of those pairings are clinically significant?

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