Reaction: Apalutamide to 1 product

Reaction
Apalutamide
DB11901
N-desmethyl apalutamide
DBMET01923
Reaction type
N-demethylation
Direction
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
active
References
  1. FDA Approved Drug Products: ERLEADA® (apalutamide) tablets, for oral use [Link]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 2C8Not AvailableNot Availableconfirmed
Cytochrome P450 3A4Not AvailableNot Availableconfirmed