Reaction: R406 to 1 product

oxidative O-demethylationMetabolism of Fostamatinib

R406 is converted to R529 by Cytochrome P450 3A4.

Reaction
R406
DBMET02094
R529
DBMET02095
Direction
Activity
inactive

What you can answer from here — as of May 04, 2018

1EnzymeEach linked to its target card
Listed above

Which other drugs are metabolised by Cytochrome P450 3A4, and which of those pairings are clinically significant?

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