Reaction: Amitriptyline to 1 product

hydroxylationMetabolism of Amitriptyline

Amitriptyline is converted to E-10-Hydroxyamitriptyline by Cytochrome P450 2D6.

Reaction
Amitriptyline
DB00321
E-10-Hydroxyamitriptyline
DBMET00051
Direction
Not Available

What you can answer from here — as of February 20, 2019

1EnzymeEach linked to its target card
Listed above
3ReferencesThe literature this reaction is curated from
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Which other drugs are metabolised by Cytochrome P450 2D6, and which of those pairings are clinically significant?

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