Reaction: Ivacaftor to 1 product
Ivacaftor is converted to M1 (hydroxymethyl-ivacaftor) by Cytochrome P450 3A4 and Cytochrome P450 3A5.
- Reaction
- Direction
- Activity
- active
What you can answer from here — as of March 26, 2019
2EnzymesEach linked to its target cardListed above
Which other drugs are metabolised by Cytochrome P450 3A4 and Cytochrome P450 3A5, and which of those pairings are clinically significant?
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