Reaction: Dextroamphetamine to 1 product

Reaction
Dextroamphetamine
DB01576
4-hydroxyamphetamine
DBMET00733
Reaction type
hydroxylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
inactive
References
  1. de la Torre R, Farre M, Navarro M, Pacifici R, Zuccaro P, Pichini S: Clinical pharmacokinetics of amfetamine and related substances: monitoring in conventional and non-conventional matrices. Clin Pharmacokinet. 2004;43(3):157-85. doi: 10.2165/00003088-200443030-00002. [Article]
  2. Brown CM, Reisfeld B, Mayeno AN: Cytochromes P450: a structure-based summary of biotransformations using representative substrates. Drug Metab Rev. 2008;40(1):1-100. doi: 10.1080/03602530802309742 . [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 2D6Not AvailableNot Availableimplied