Reaction: Levodopa to 1 product
- Reaction
- Reaction type
- oxidative decarboxylation
- Direction
- Major circulating metabolite?
- Yes
- Spontaneous?
- No
- Activity
- active
- References
- Elroby SA, Makki MS, Sobahi TR, Hilal RH: Toward the understanding of the metabolism of levodopa I. DFT investigation of the equilibrium geometries, acid-base properties and levodopa-water complexes. Int J Mol Sci. 2012;13(4):4321-39. doi: 10.3390/ijms13044321. Epub 2012 Apr 2. [Article]
- Goodall M, Alton H: Metabolism of 3,4-dihydroxyphenylalanine (L-dopa) in human subjects. Biochem Pharmacol. 1972 Sep 1;21(17):2401-8. [Article]
- Meiser J, Weindl D, Hiller K: Complexity of dopamine metabolism. Cell Commun Signal. 2013 May 17;11(1):34. doi: 10.1186/1478-811X-11-34. [Article]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Aromatic-L-amino-acid decarboxylase Not Available Not Available implied
