Reaction: Ketoconazole ketone hydroxyl intermediate to 1 product
N-dealkylationMetabolism of Ketoconazole
Ketoconazole ketone hydroxyl intermediate is converted to M2 (Ketoconazole) by Cytochrome P450 3A4 and Cytochrome P450 2D6.
- Reaction
- Direction
- Activity
- inactive
What you can answer from here — as of July 30, 2019
2EnzymesEach linked to its target cardListed above
Which other drugs are metabolised by Cytochrome P450 3A4 and Cytochrome P450 2D6, and which of those pairings are clinically significant?
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