Reaction: 4-Hydroxytamoxifen to 1 product
N-dealkylationMetabolism of Tamoxifen
4-Hydroxytamoxifen is converted to Endoxifen (4-hydroxy-N-desmethyltamoxifen) by Cytochrome P450 3A4 and Cytochrome P450 3A5.
- Reaction
- Direction
- Activity
- active
What you can answer from here — as of August 06, 2019
2EnzymesEach linked to its target cardListed above
Which other drugs are metabolised by Cytochrome P450 3A4 and Cytochrome P450 3A5, and which of those pairings are clinically significant?
Create a free account or log in to explore the full data card.
Create Account