Reaction: Cyclobenzaprine to 1 product

Reaction
Cyclobenzaprine
DB00924
Cyclobenzaprine N+-Glucuronide
DBMET02774
Reaction type
N-glucuronidation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Lu D, Xie Q, Wu B: N-glucuronidation catalyzed by UGT1A4 and UGT2B10 in human liver microsomes: Assay optimization and substrate identification. J Pharm Biomed Anal. 2017 Oct 25;145:692-703. doi: 10.1016/j.jpba.2017.07.037. Epub 2017 Aug 4. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
UDP-glucuronosyltransferase 1-4Not AvailableNot Availableimplied
UDP-glucuronosyltransferase 2B10Not AvailableNot Availableimplied