Reaction: Filgotinib to 1 product

hydrolysisMajor circulating metaboliteMetabolism of Filgotinib

Filgotinib is converted to GS-829845 by Cocaine esterase and Liver carboxylesterase 1.

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What you can answer from here — as of October 13, 2020

2EnzymesEach linked to its target card
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3ReferencesThe literature this reaction is curated from
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Which other drugs are metabolised by Cocaine esterase and Liver carboxylesterase 1, and which of those pairings are clinically significant?

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