Reaction: Oxymetazoline to 1 product

Reaction
Oxymetazoline
DB00935
Oxymetazoline O-glucuronide
DBMET03228
Reaction type
O-glucuronidation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Mahajan MK, Uttamsingh V, Gan LS, Leduc B, Williams DA: Identification and characterization of oxymetazoline glucuronidation in human liver microsomes: evidence for the involvement of UGT1A9. J Pharm Sci. 2011 Feb;100(2):784-93. doi: 10.1002/jps.22303. [Article]
  2. FDA Approved Drug Products: KOVANAZE (tetracaine HCl and oxymetazoline HCl) Nasal Spray [Link]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
UDP-glucuronosyltransferase 1-9Not AvailableNot Availableconfirmed