Reaction: Melphalan flufenamide to 1 product

Reaction
Melphalan flufenamide
DB16627
Melphalan
DB01042
Reaction type
Not Available
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
active
References
  1. Wickstrom M, Nygren P, Larsson R, Harmenberg J, Lindberg J, Sjoberg P, Jerling M, Lehmann F, Richardson P, Anderson K, Chauhan D, Gullbo J: Melflufen - a peptidase-potentiated alkylating agent in clinical trials. Oncotarget. 2017 Jun 8;8(39):66641-66655. doi: 10.18632/oncotarget.18420. eCollection 2017 Sep 12. [Article]
  2. FDA Approved Drug Products: Pepaxto (Melphalan Flufenamide) Intravenous Injection [Link]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Aminopeptidase NNot AvailableNot Availableimplied