Reaction: Eliglustat to 1 product

Reaction
Eliglustat
DB09039
Genz-311752
DBMET03452
Reaction type
oxidation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
inactive
References
  1. FDA Pharmacology Review: Cerdelga (eliglustat) oral capsules [Link]
  2. FDA Clinical Pharmacology Biopharmaceutics Review: Cerdelga (eliglustat) oral capsules [Link]
Comments
Proposed metabolic pathway of oxidation.
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 2D6Not AvailableNot Availableconfirmed
Cytochrome P450 3A4Not AvailableNot Availableconfirmed