Reaction: R-4'-hydroxybupropion to 1 product

Reaction
Reaction type
ketoreduction
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
Not Available
Comments
Aflatoxin B1 aldehyde reductase member 3 (AKR7) is the main enzyme that catalyzes the reaction in the intestine, while corticosteroid 11-beta dehydrogenase (HSD11B1) is the main enzyme responsible in the liver.[A247010]
Enzymes
EnzymeKmVmaxRole
Corticosteroid 11-beta-dehydrogenase isozyme 1Not AvailableNot Availableimplied
Aflatoxin B1 aldehyde reductase member 3Not AvailableNot Availableimplied