Aldo-keto reductase family 7 member A3

BE0009799ProteinHumansAKR7A3

Catalyzes the NADPH-dependent reduction of various carbonyl-containing compounds, including aldehydes, ketones, and toxic products from cellular metabolism or environmental exposure.

Gene name
AKR7A3
UniProtKB entry
O95154Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
331 residues · 37,206 Da
Also known as
1.1.1.2 · AFAR2 · AFB1 aldehyde reductase 2 · AFB1-AR 2 · Aflatoxin B1 aldehyde reductase member 3

Resolves to

Protein
UniProtO95154UniProt nameARK73_HUMAN
Gene
HGNCHGNC:390NCBI Gene22977GeneCardsAKR7A3
Pharmacology
KEGGhsa:22977
Structure
PDB2CLP

What you can answer from here — as of June 26, 2025

8Metabolic reactionsDrug transformations it catalyses, substrate to product
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
6+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Aldo-keto reductase family 7 member A3, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In