Reaction: Dabrafenib to 1 product

Aliphatic hydroxylationMajor circulating metaboliteMetabolism of Dabrafenib

Dabrafenib is converted to Hydroxy-dabrafenib by Cytochrome P450 3A4 and Cytochrome P450 2C8.

Direction
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active

What you can answer from here — as of June 08, 2022

2EnzymesEach linked to its target card
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4ReferencesThe literature this reaction is curated from
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Which other drugs are metabolised by Cytochrome P450 3A4 and Cytochrome P450 2C8, and which of those pairings are clinically significant?

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