Reaction: Sulfasalazine to 2 products

reductive cleavageMajor circulating metaboliteMetabolism of Sulfasalazine

Sulfasalazine is converted to Mesalazine and Sulfapyridine.

Direction
Activity
active
Comments
The reaction was catalyzed by azoreductase enzyme by colonic bacteria.[A255136]

What you can answer from here — as of December 21, 2022

1ReferenceThe literature this reaction is curated from
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Which metabolites of Sulfasalazine are active, and how do they change its interactions?

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