Reaction: Bexagliflozin to 1 product

Reaction
Reaction type
O-glucuronidation
Direction
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
inactive
References
  1. Zhang W, Li X, Ding H, Lu Y, Stilwell GE, Halvorsen YD, Welihinda A: Metabolism and disposition of the SGLT2 inhibitor bexagliflozin in rats, monkeys and humans. Xenobiotica. 2020 May;50(5):559-569. doi: 10.1080/00498254.2019.1654634. Epub 2019 Aug 27. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
UDP-glucuronosyltransferase 1-9Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 1-1Not AvailableNot Availableconfirmed