Reaction: Ivacaftor to 1 product
carboxylationMetabolism of Ivacaftor
Ivacaftor is converted to M6 (ivacaftor-carboxylate) by Cytochrome P450 3A4 and Cytochrome P450 3A5.
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What you can answer from here — as of April 20, 2023
2EnzymesEach linked to its target cardListed above
Which other drugs are metabolised by Cytochrome P450 3A4 and Cytochrome P450 3A5, and which of those pairings are clinically significant?
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