Reaction: SN-38 to 1 product

glucuronidationMetabolism of Irinotecan

SN-38 is converted to SN-38G by UDP-glucuronosyltransferase 1A1.

Reaction
SN-38
DBMET01143
SN-38G
DBMET03770
Direction

What you can answer from here — as of March 25, 2024

1EnzymeEach linked to its target card
Listed above

Which other drugs are metabolised by UDP-glucuronosyltransferase 1A1, and which of those pairings are clinically significant?

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