Reaction: Irinotecan to 1 product

oxidationMetabolism of Irinotecan

Irinotecan is converted to APC by Cytochrome P450 3A4.

Reaction
Irinotecan
DB00762
APC
DBMET03771
Direction
Activity
inactive
Comments
APC is a weak topoisomerase I inhibitor.

What you can answer from here — as of March 25, 2024

1EnzymeEach linked to its target card
Listed above
2ReferencesThe literature this reaction is curated from
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Which other drugs are metabolised by Cytochrome P450 3A4, and which of those pairings are clinically significant?

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