Reaction: Clorazepic acid to 1 product

Reaction
Clorazepic acid
DB00628
Nordazepam
DB14028
Reaction type
decarboxylation
Direction
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
active
References
  1. Smolders EJ, de Kanter CT, de Knegt RJ, van der Valk M, Drenth JP, Burger DM: Drug-Drug Interactions Between Direct-Acting Antivirals and Psychoactive Medications. Clin Pharmacokinet. 2016 Dec;55(12):1471-1494. doi: 10.1007/s40262-016-0407-2. [Article]
  2. FDA Approved Drug Products: Tranxene T-TAB (clorazepate dipotassium) tablets for oral use [Link]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 3A4Not AvailableNot Availableimplied