Cefmetazole sodiumProduct ingredient for Cefmetazole
- Name
- Cefmetazole sodium
- Drug Entry
- Cefmetazole
A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.
- Accession Number
- DBSALT000391
- Structure
Structure for Cefmetazole sodium (DBSALT000391)
- Synonyms
- Not Available
- UNII
- 37Y9VR4W7A
- CAS Number
- 56796-39-5
- Weight
- Average: 493.516
Monoisotopic: 493.027273402 - Chemical Formula
- C15H16N7NaO5S3
- InChI Key
- BITQGIOJQWZUPL-UHFFFAOYSA-M
- InChI
- InChI=1S/C15H17N7O5S3.Na/c1-21-14(18-19-20-21)30-6-8-5-29-13-15(27-2,17-9(23)7-28-4-3-16)12(26)22(13)10(8)11(24)25;/h13H,4-7H2,1-2H3,(H,17,23)(H,24,25);/q;+1/p-1
- IUPAC Name
- sodium N-[(6R,7S)-2-carboxy-7-methoxy-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-7-yl]-2-[(cyanomethyl)sulfanyl]ethanimidate
- SMILES
- [Na+].[H][C@]12SCC(CSC3=NN=NN3C)=C(N1C(=O)[C@@]2(OC)N=C([O-])CSCC#N)C(O)=O
- External Links
- KEGG Compound
- C08104
- PubChem Compound
- 23666711
- ChemSpider
- 10608662
- ChEBI
- 3490
- Wikipedia
- Cefmetazole
- Predicted Properties
Property Value Source Water Solubility 1.32 mg/mL ALOGPS logP 0.26 ALOGPS logP 0.17 Chemaxon logS -2.6 ALOGPS pKa (Strongest Acidic) 3.12 Chemaxon pKa (Strongest Basic) -1.7 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 10 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 169.65 Å2 Chemaxon Rotatable Bond Count 9 Chemaxon Refractivity 135.64 m3·mol-1 Chemaxon Polarizability 43.7 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon