Diphenidol hydrochlorideProduct ingredient for Diphenidol
- Name
- Diphenidol hydrochloride
- Drug Entry
- Diphenidol
Diphenidol is an antiemetic agent used in the treatment of vomiting and vertigo. Diphenidol overdose may result in serious toxicity in children.
- Accession Number
- DBSALT000395
- Structure
- Synonyms
- Diphenidol HCl
- UNII
- DG355XWQ4T
- CAS Number
- 3254-89-5
- Weight
- Average: 345.906
Monoisotopic: 345.18594223 - Chemical Formula
- C21H28ClNO
- InChI Key
- AVZIYZHXZAYGJS-UHFFFAOYSA-N
- InChI
- InChI=1S/C21H27NO.ClH/c23-21(19-11-4-1-5-12-19,20-13-6-2-7-14-20)15-10-18-22-16-8-3-9-17-22;/h1-2,4-7,11-14,23H,3,8-10,15-18H2;1H
- IUPAC Name
- 1,1-diphenyl-4-(piperidin-1-yl)butan-1-ol hydrochloride
- SMILES
- Cl.OC(CCCN1CCCCC1)(C1=CC=CC=C1)C1=CC=CC=C1
- External Links
- PubChem Compound
- 66266
- ChemSpider
- 59647
- ChEBI
- 31481
- ChEMBL
- CHEMBL1529
- Wikipedia
- Diphenidol
- Predicted Properties
Property Value Source Water Solubility 0.00587 mg/mL ALOGPS logP 4.08 ALOGPS logP 4.22 Chemaxon logS -4.7 ALOGPS pKa (Strongest Acidic) 13.4 Chemaxon pKa (Strongest Basic) 9.23 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 23.47 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 96.92 m3·mol-1 Chemaxon Polarizability 37.03 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule Yes Chemaxon