Diphenidol hydrochlorideProduct ingredient for Diphenidol

Name
Diphenidol hydrochloride
Drug Entry
Diphenidol

Diphenidol is an antiemetic agent used in the treatment of vomiting and vertigo. Diphenidol overdose may result in serious toxicity in children.

Accession Number
DBSALT000395
Structure
Synonyms
Diphenidol HCl
UNII
DG355XWQ4T
CAS Number
3254-89-5
Weight
Average: 345.906
Monoisotopic: 345.18594223
Chemical Formula
C21H28ClNO
InChI Key
AVZIYZHXZAYGJS-UHFFFAOYSA-N
InChI
InChI=1S/C21H27NO.ClH/c23-21(19-11-4-1-5-12-19,20-13-6-2-7-14-20)15-10-18-22-16-8-3-9-17-22;/h1-2,4-7,11-14,23H,3,8-10,15-18H2;1H
IUPAC Name
1,1-diphenyl-4-(piperidin-1-yl)butan-1-ol hydrochloride
SMILES
Cl.OC(CCCN1CCCCC1)(C1=CC=CC=C1)C1=CC=CC=C1
PubChem Compound
66266
ChemSpider
59647
ChEBI
31481
ChEMBL
CHEMBL1529
Wikipedia
Diphenidol
Predicted Properties
PropertyValueSource
Water Solubility0.00587 mg/mLALOGPS
logP4.08ALOGPS
logP4.22Chemaxon
logS-4.7ALOGPS
pKa (Strongest Acidic)13.4Chemaxon
pKa (Strongest Basic)9.23Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area23.47 Å2Chemaxon
Rotatable Bond Count6Chemaxon
Refractivity96.92 m3·mol-1Chemaxon
Polarizability37.03 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleYesChemaxon