Ampicillin sodiumProduct ingredient for Ampicillin
- Name
- Ampicillin sodium
- Drug Entry
- Ampicillin
Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
- Accession Number
- DBSALT000533
- Structure
- Synonyms
- Ampicillin (as sodium) / Ampicillinum natricum
- UNII
- JFN36L5S8K
- CAS Number
- 69-52-3
- Weight
- Average: 371.387
Monoisotopic: 371.091571444 - Chemical Formula
- C16H18N3NaO4S
- InChI Key
- KLOHDWPABZXLGI-UHFFFAOYSA-M
- InChI
- InChI=1S/C16H19N3O4S.Na/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);/q;+1/p-1
- IUPAC Name
- sodium (2R)-2-amino-N-[(2S,5R,6R)-2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-6-yl]-2-phenylethanimidate
- SMILES
- [Na+].[H][C@](N)(C([O-])=N[C@]1([H])C(=O)N2[C@]1([H])SC(C)(C)[C@]2([H])C(O)=O)C1=CC=CC=C1
- External Links
- KEGG Drug
- D02119
- KEGG Compound
- C13652
- PubChem Compound
- 23663979
- ChemSpider
- 6012
- ChEBI
- 34535
- ChEMBL
- CHEMBL1320119
- Wikipedia
- Ampicillin
- Predicted Properties
Property Value Source Water Solubility 0.269 mg/mL ALOGPS logP 0.93 ALOGPS logP -1.4 Chemaxon logS -3.1 ALOGPS pKa (Strongest Acidic) 2.8 Chemaxon pKa (Strongest Basic) 8.42 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 119.05 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 98.6 m3·mol-1 Chemaxon Polarizability 33.95 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon