Darunavir ethanolateProduct ingredient for Darunavir

Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection.¹⁷ As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.^2,5 It was initially approved by the FDA in 2006.¹⁷

Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19, due to in vitro evidence supporting its ability to combat this infection.¹⁴ Clinical trials are underway and are expected to conclude in August 2020.¹⁹