Levacetylmethadol hydrochlorideProduct ingredient for Levacetylmethadol
- Name
- Levacetylmethadol hydrochloride
- Drug Entry
- Levacetylmethadol
Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence.
Levacetylmethadol was withdrawn from use in the European Union due to its high risk of QT interval prolongation. The production of levacetylmethadol in the US has ceased as well.2,1
- Accession Number
- DBSALT001444
- Structure
Structure for Levacetylmethadol hydrochloride (DBSALT001444)
- Synonyms
- Levomethadyl acetate HCl / Levomethadyl Acetate Hydrochloride
- UNII
- B54CW5KG52
- CAS Number
- 43033-72-3
- Weight
- Average: 389.96
Monoisotopic: 389.212157 - Chemical Formula
- C23H32ClNO2
- InChI Key
- UXBPQRGCVJOTNT-COBSGTNCSA-N
- InChI
- InChI=1S/C23H31NO2.ClH/c1-6-22(26-19(3)25)23(17-18(2)24(4)5,20-13-9-7-10-14-20)21-15-11-8-12-16-21;/h7-16,18,22H,6,17H2,1-5H3;1H/t18-,22-;/m0./s1
- IUPAC Name
- (3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate hydrochloride
- SMILES
- Cl.CC[C@H](OC(C)=O)C(C[C@H](C)N(C)C)(C1=CC=CC=C1)C1=CC=CC=C1
- External Links
- ChemSpider
- 36016
- ChEBI
- 6442
- ChEMBL
- CHEMBL1200817
- Wikipedia
- Levacetylmethadol
- Predicted Properties
Property Value Source Water Solubility 0.00179 mg/mL ALOGPS logP 4.78 ALOGPS logP 4.88 Chemaxon logS -5.3 ALOGPS pKa (Strongest Basic) 9.87 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 29.54 Å2 Chemaxon Rotatable Bond Count 9 Chemaxon Refractivity 117.86 m3·mol-1 Chemaxon Polarizability 40.64 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon