Cefonicid sodiumProduct ingredient for Cefonicid
- Name
- Cefonicid sodium
- Drug Entry
- Cefonicid
A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
- Accession Number
- DBSALT001472
- Structure
- Synonyms
- Not Available
- UNII
- F74MFL78A1
- CAS Number
- 61270-78-8
- Weight
- Average: 586.52
Monoisotopic: 585.99871358 - Chemical Formula
- C18H16N6Na2O8S3
- InChI Key
- NAXFZVGOZUWLEP-RFXDPDBWSA-L
- InChI
- InChI=1S/C18H18N6O8S3.2Na/c25-13(9-4-2-1-3-5-9)14(26)19-11-15(27)24-12(17(28)29)10(6-33-16(11)24)7-34-18-20-21-22-23(18)8-35(30,31)32;;/h1-5,11,13,16,25H,6-8H2,(H,19,26)(H,28,29)(H,30,31,32);;/q;2*+1/p-2/t11-,13-,16-;;/m1../s1
- IUPAC Name
- disodium (6R,7R)-7-{[(2R)-2-hydroxy-1-oxido-2-phenylethylidene]amino}-8-oxo-3-({[1-(sulfomethyl)-1H-1,2,3,4-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- SMILES
- [Na+].[Na+].[H][C@](O)(C([O-])=N[C@]1([H])C(=O)N2C(C([O-])=O)=C(CSC3=NN=NN3CS(O)(=O)=O)CS[C@]12[H])C1=CC=CC=C1
- External Links
- KEGG Compound
- C08105
- ChemSpider
- 39733
- ChEBI
- 3492
- ChEMBL
- CHEMBL1201005
- Wikipedia
- Cefonicid
- Predicted Properties
Property Value Source Water Solubility 1.17 mg/mL ALOGPS logP -0.04 ALOGPS logP -1.7 Chemaxon logS -2.7 ALOGPS pKa (Strongest Acidic) -1.5 Chemaxon pKa (Strongest Basic) -0.64 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 12 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 214.06 Å2 Chemaxon Rotatable Bond Count 9 Chemaxon Refractivity 158.48 m3·mol-1 Chemaxon Polarizability 48.69 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon