Piperazine phosphateProduct ingredient for Piperazine
- Name
- Piperazine phosphate
- Drug Entry
- Piperazine
Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 1953. Upon entry into the systemic circulation, the drug is partly oxidized and partly eliminated as an unchanged compound. Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. Piperazine was first introduced as an anthelmintic in 1953. Piperazine compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism.
- Accession Number
- DBSALT001633
- Structure
Structure for Piperazine phosphate (DBSALT001633)
- Synonyms
- Not Available
- UNII
- 8TIF7T48FP
- CAS Number
- 18534-18-4
- Weight
- Average: 202.147
Monoisotopic: 202.071858589 - Chemical Formula
- C4H15N2O5P
- InChI Key
- PMGABIJVFLPSLS-UHFFFAOYSA-N
- InChI
- InChI=1S/C4H10N2.H3O4P.H2O/c1-2-6-4-3-5-1;1-5(2,3)4;/h5-6H,1-4H2;(H3,1,2,3,4);1H2
- IUPAC Name
- phosphoric acid piperazine hydrate
- SMILES
- O.OP(O)(O)=O.C1CNCCN1
- External Links
- KEGG Compound
- C12839
- ChemSpider
- 392013
- ChEBI
- 32006
- ChEMBL
- CHEMBL2105892
- Predicted Properties
Property Value Source Water Solubility 16.0 mg/mL ALOGPS logP -0.96 ALOGPS logP -0.73 Chemaxon logS -0.79 ALOGPS pKa (Strongest Basic) 9.56 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 24.06 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 25.45 m3·mol-1 Chemaxon Polarizability 9.88 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon