Robenidine hydrochlorideProduct ingredient for Robenidine

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Name
Robenidine hydrochloride
Drug Entry
Robenidine

Robenidine is identified as a coccidiostat drug, which slows both the growth and reproductive cycles of coccidian parasites. Robenidine is used to control coccidiosis, a lethal infection in poultry which has shown a significant economic burden. Despite the availability of other agents to treat coccidiosis, robenidine has been proven to be effective in delaying the development of antibiotic resistance through intermittent and rotating use with other antimicrobials. Farmers alternate the use of robenidine with other antimicrobial agents in order to maintain effectiveness by slowing the development of antimicrobial resistance.

See full entry for Robenidine
Accession Number
DBSALT001699
Structure
Similar Structures
Synonyms
Robenidine HCl / Robenidine hydrochloride
UNII
8STT15Y392
CAS Number
25875-50-7
Weight
Average: 370.66
Monoisotopic: 369.0314786
Chemical Formula
C15H14Cl3N5
InChI Key
LTWIBTYLSRDGHP-HCURTGQUSA-N
InChI
InChI=1S/C15H13Cl2N5.ClH/c16-13-5-1-11(2-6-13)9-19-21-15(18)22-20-10-12-3-7-14(17)8-4-12;/h1-10H,(H3,18,21,22);1H/b19-9+,20-10+;
IUPAC Name
{bis[(2E)-2-[(4-chlorophenyl)methylidene]hydrazin-1-yl]methylidene}azanium chloride
SMILES
[Cl-].ClC1=CC=C(\C=N\NC(=[NH2+])N\N=C\C2=CC=C(Cl)C=C2)C=C1
ChemSpider
7844904
ChEMBL
CHEMBL2106896
Predicted Properties
PropertyValueSource
Water Solubility0.00224 mg/mLALOGPS
logP3.01ALOGPS
logP4.38Chemaxon
logS-5.2ALOGPS
pKa (Strongest Acidic)14.71Chemaxon
pKa (Strongest Basic)4.99Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count4Chemaxon
Hydrogen Donor Count3Chemaxon
Polar Surface Area74.37 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity123.45 m3·mol-1Chemaxon
Polarizability34.34 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon