Lysine hydrochlorideProduct ingredient for Lysine
- Name
- Lysine hydrochloride
- Drug Entry
- Lysine
Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
- Accession Number
- DBSALT001756
- Structure
Structure for Lysine hydrochloride (DBSALT001756)
- Synonyms
- L-Lysine HCl / L-Lysine hydrochloride / Lysine HCl / Lysine hydrochloride
- UNII
- JNJ23Q2COM
- CAS Number
- 657-27-2
- Weight
- Average: 182.649
Monoisotopic: 182.082205441 - Chemical Formula
- C6H15ClN2O2
- InChI Key
- BVHLGVCQOALMSV-JEDNCBNOSA-N
- InChI
- InChI=1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1
- IUPAC Name
- (2S)-2,6-diaminohexanoic acid hydrochloride
- SMILES
- Cl.NCCCC[C@H](N)C(O)=O
- External Links
- ChemSpider
- 62772
- ChEBI
- 53633
- ChEMBL
- CHEMBL2105886
- Wikipedia
- Lysine
- Predicted Properties
Property Value Source Water Solubility 105.0 mg/mL ALOGPS logP -3.8 ALOGPS logP -3.2 ChemAxon logS -0.14 ALOGPS pKa (Strongest Acidic) 2.74 ChemAxon pKa (Strongest Basic) 10.29 ChemAxon Physiological Charge 1 ChemAxon Hydrogen Acceptor Count 4 ChemAxon Hydrogen Donor Count 3 ChemAxon Polar Surface Area 89.34 Å2 ChemAxon Rotatable Bond Count 5 ChemAxon Refractivity 37.81 m3·mol-1 ChemAxon Polarizability 15.84 Å3 ChemAxon Number of Rings 0 ChemAxon Bioavailability 1 ChemAxon Rule of Five Yes ChemAxon Ghose Filter No ChemAxon Veber's Rule No ChemAxon MDDR-like Rule No ChemAxon