Dexetimide hydrochlorideProduct ingredient for Dexetimide
- Name
- Dexetimide hydrochloride
- Drug Entry
- Dexetimide
A muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.
- Accession Number
- DBSALT002920
- Structure
Structure for Dexetimide hydrochloride (DBSALT002920)
- Synonyms
- Dexetimide HCl / Dextrobenzetimide hydrochloride
- External IDs
- R 16470
- UNII
- B987A3XX7D
- CAS Number
- 21888-96-0
- Weight
- Average: 398.93
Monoisotopic: 398.1761058 - Chemical Formula
- C23H27ClN2O2
- InChI Key
- XSOOSXRNMDUWEM-GNAFDRTKSA-N
- InChI
- InChI=1S/C23H26N2O2.ClH/c26-21-11-14-23(22(27)24-21,19-9-5-2-6-10-19)20-12-15-25(16-13-20)17-18-7-3-1-4-8-18;/h1-10,20H,11-17H2,(H,24,26,27);1H/t23-;/m1./s1
- IUPAC Name
- (3S)-1'-benzyl-2,6-dioxo-3-phenyl-[3,4'-bipiperidin]-1'-ium chloride
- SMILES
- [Cl-].O=C1CC[C@@](C2CC[NH+](CC3=CC=CC=C3)CC2)(C(=O)N1)C1=CC=CC=C1
- External Links
- ChemSpider
- 28614
- Predicted Properties
Property Value Source Water Solubility 6.09e-05 mg/mL ALOGPS logP 0.73 ALOGPS logP 3.38 Chemaxon logS -6.8 ALOGPS pKa (Strongest Acidic) 11.69 Chemaxon pKa (Strongest Basic) 8.66 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 50.61 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 117.36 m3·mol-1 Chemaxon Polarizability 40.66 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon