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Displaying results 91 - 93 of 93 in total
  1. Target

    Complement C1q subcomponent subunit C

    go.drugbank.com/bio_entities/BE0002096
    TargetHumans

    Immunoglobulin-binding activates the proenzyme C1R, which cleaves C1S, initiating the proteolytic cascade of the complement system (PubMed:29449492). … The classical complement pathway is initiated by the C1Q subcomplex of the C1 complex, which specifically binds IgG or IgM immunoglobulins complexed with antigens, forming antigen-antibody complexes on

  2. Target

    Complement component 1q (C1q)

    go.drugbank.com/bio_entities/BE0009995
    TargetHumans

    Immunoglobulin-binding activates the proenzyme C1R, which cleaves C1S, initiating the proteolytic cascade of the complement system (PubMed:29449492). … Immunoglobulin-binding activates the proenzyme C1R, which cleaves C1S, initiating the proteolytic cascade of the complement system (PubMed:29449492).

  3. Target

    Interleukin-5

    go.drugbank.com/bio_entities/BE0001208
    TargetHumans

    Also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity).