Complement C1q subcomponent subunit C

BE0002096ProteinHumansC1QC

Core component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens... It is acted on by 9 drugs in DrugBank.

Gene name
C1QC
UniProtKB entry
P02747Swiss-Prot
Cellular location
Secreted
Residues / weight
245 residues · 25,774 Da
Also known as
C1QG

Resolves to

Protein
UniProtP02747UniProt nameC1QC_HUMAN
Gene
HGNCHGNC:1245NCBI Gene714GenBank33150626GeneCardsC1QC
Pharmacology
KEGGhsa:714
Structure
PDB1PK6PDB2JG8PDB2JG9
Drugs

What you can answer from here — as of September 07, 2019

9DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Complement C1q subcomponent subunit C, how selective are they, and which programs against it are still in active trials?

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