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Displaying results 91 - 100 of 9220 in total
  1. Drug

    Rivabazumab pegol

    go.drugbank.com/drugs/DB17788
    Investigational

    Rivabazumab pegol is being investigated as a treatment of Pseudomonas aeruginosa lung infections in patients with cystic fibrosis.

    Synonyms: KB001-A (AN ANTI-PCRV PEGYLATED MONOCLONAL ANTIBODY FRAGMENT TO THE TYPE III SECRETION SYSTEM OF PSEUDOMONAS AERUGINOSA)
  2. Drug

    Acazicolcept

    go.drugbank.com/drugs/DB18410
    Investigational

    Synonyms: HUMAN INDUCIBLE T-CELL CO-STIMULATOR LIGAND (ICOS LIGAND) N-TERMINAL FRAGMENT (1-122) (VARIANT (N52>H, N57>Y, Q100>R), FUSED VIA PEPTIDYL LINKER 123GGGGSGGGGS132 TO A HUMAN IMMUNOGLOBULIN G1 FC FRAGMENT, Fc fusion protein of a human inducible T cell costimulator ligand variant immunoglobulin domain designed to inhibit simultaneously the CD28 and ICOS inflammation pathways
  3. Drug

    Dezamizumab

    go.drugbank.com/drugs/DB15153
    Investigational

    Dezamizumab is under investigation in clinical trial NCT03417830 (Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging).

    Synonyms: recombinant monoclonal antibody to human serum amyloid P component
  4. Drug

    Taniraleucel

    go.drugbank.com/drugs/DB18311
    Investigational

    Synonyms: The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell
  5. Drug

    Acetylcysteine

    go.drugbank.com/drugs/DB06151
    ApprovedInvestigational

    Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of [acetaminophen] overdose. … [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.

    Mixtures: ASIST C 600 MG-300 MG TOZ IÇEREN SAŞE,20 SAŞE, ASIST C 600 MG-300 MG TOZ IÇEREN SAŞE,30 SAŞECategories: Antidote for Acetaminophen Overdose, Compounds used in a research, industrial, or household setting
  6. Drug

    Tavokinogene telseplasmid

    go.drugbank.com/drugs/DB17301
    Investigational

    Tavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12.

    Synonyms: Dna plasmid containing genes coding for the human interleukin 12 (il-12) p35 and p40 subunits that are separated by an internal ribosomal entry site (ires) and under the control of a single cytomegalovirus
  7. Pathway

    Cabergoline Mechanism of Action Action Pathway

    smpdb.ca/view/SMP0126670
    Drug action

    Cabergoline stimulates centrally-located dopaminergic D2- and D3-receptors. Cabergoline is a long-acting agonist with a high affinity for D2 receptors. … Cabergoline is often used in patients who cannot tolerate the adverse effects of bromocriptine or in those who do not respond to bromocriptine.

    Drugs: Pyridoxal phosphate · Tyrosine · Cabergoline · Dopamine · Levodopa · Calcium +2 more
  8. Drug

    Zirconium (89Zr) crefmirlimab berdoxam

    go.drugbank.com/drugs/DB19157
    Investigational

    Synonyms: Iab22m2c (antibody fragment against the human cd8-antigen on cd8-positive t-cells, conjugated to the chelator desferrioxamine (df) and labeled with the radioisotope zirconium Zr-89)
  9. Drug

    Archexin

    go.drugbank.com/drugs/DB05971
    Investigational

    Synonyms: 20-mer complementary to Akt mRNA, 5'-DG-DC-T-DG-DC-DA-T-DG-DA-T-DC-T-DC-DC-T-T-DG-DG-DC-DG-3'
  10. Drug

    Iodine I-131 monoclonal antibody 81C6

    go.drugbank.com/drugs/DB16197
    Investigational

    Neuradiab is under investigation in clinical trial NCT00615186 (Glioblastoma Multiforme (GBM) Locoregional Agent Survival Study - Anti-tenascin Radiolabeled Antibody Therapy).

    Synonyms: Moab, 81c6, murine, iodine-I-131 radiolabeled, to human glioma