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Displaying results 91 - 100 of 13103 in total
  1. Drug

    Varicella zoster vaccine (live/attenuated)

    go.drugbank.com/drugs/DB10318
    ApprovedInvestigational

    Since October 2017, however, it has been replaced as first line therapy by Shingrix ([DB13924]), a more effective and longer lasting vaccine[L1038]. … Clinical trials for Shingrix have shown greater than 90% efficacy in adults aged 50 and older, with 89% efficacy in preventing postherpetic neuralgia in patients 70 years and older and 91% efficacy in

    Mixtures: Priorix - Tetra Pulver in einer Durchstechflasche und Lösungsmittel in einer Fertigspritze zur Herstellung einer InjektionslösungProducts: Varilrix Pulver und Lösungsmittel zur Herstellung einer Injektionssuspension in einer Fertigspritze, VARIVAX Pulver und Lösungsmittel zur Herstellung einer Injektionssuspension in einer Fertigspritze
  2. Drug

    Clostridium tetani toxoid antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB10583
    ApprovedInvestigational

    The toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium sulfate filtration and precipation. … It is used for active immunization of children 7 years of age or older, and adults, for prevention of tetanus.

    Mixtures: -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE, Repevax Injektionssuspension in einer FertigspritzeProducts: TETAVAX single dose, suspension for injection in a prefilled syringe, Tetanus Toxoid Adsorbed Inj
  3. Drug

    Insulin glargine

    go.drugbank.com/drugs/DB00047
    ApprovedInvestigational

    Insulin glargine is also available as the biosimilar, or "follow-on" product, Basaglar in the US and as Abasaglar in the EU. … Insulin is an important treatment in the management of Type 1 Diabetes (T1D), which is caused by an autoimmune reaction that destroys the beta cells of the pancreas, resulting in the body not being able

    Mixtures: SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 50MCG/ML, SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 33MCG/MLCategories: Drugs Used in Diabetes
  4. Drug

    Ceftazidime

    go.drugbank.com/drugs/DB00438
    ApprovedInvestigational

    [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone or in combination with the non-β-lactam β-lactamase inhibitor [avibactam] to treat a variety of … [A232920] β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ultimately

    Products: CEFTAZIDIMA ORCHID EUROPE, Ceptaz Injection - Pws Im IV 1g/vial
  5. Target

    Melanoma antigen preferentially expressed in tumors

    go.drugbank.com/bio_entities/BE0010493
    TargetHumans

    In the nucleus, the CRL2(PRAME) complex is recruited to epigenetically and transcriptionally active promoter regions bound by nuclear transcription factor Y (NFY) and probably plays a role in chromstin

    Polypeptides: Melanoma antigen preferentially expressed in tumors
  6. Drug

    Piperacillin

    go.drugbank.com/drugs/DB00319
    ApprovedInvestigational

    It is also used in combination with other antibiotics.

    Mixtures: Zosyn in Galaxy Containers, Zosyn in Galaxy ContainersProducts: Pipracil-pws IV Im 2g/vial, Pipracil-pws IV Im 3g/vial
  7. Drug

    Iohexol

    go.drugbank.com/drugs/DB01362
    ApprovedInvestigational

    Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. … Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: N,N'-Bis(2,3-dihydroxypropyl)-5-(N-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamide
  8. Drug

    Haloperidol

    go.drugbank.com/drugs/DB00502
    ApprovedInvestigational

    [A180625] The efficacy of haloperidol was first established in controlled trials in the 1960s.[A180610] … However, these findings contradict the findings from studies in vitro with human liver microsomes and from drug interaction studies in vivo.

    Products: MYUNG IN HALOPERIDOL TABLET 1.5 mg, MYUNG IN HALOPERIDOL INJECTION 5 mg/ml
  9. Drug

    Infliximab

    go.drugbank.com/drugs/DB00065
    ApprovedInvestigational

    Infliximab is produced by a recombinant cell line cultured by continuous perfusion. … alternative first-line therapies for that disorder [FDA Label].

    Products: Remsima 120mg solution for injection in pre-filled pen, Remsima 120mg solution for injection in pre-filled syringe
  10. Target

    Membrane protein involved in aromatic hydrocarbon degradation

    go.drugbank.com/bio_entities/BE0003979
    TargetPseudomonas putida (strain F1 / ATCC 700007)

    Polypeptides: Membrane protein involved in aromatic hydrocarbon degradation