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Pravastatin
go.drugbank.com/drugs/DB00175ApprovedInvestigationalIt was the first statin administered as the active form and not as a prodrug.[T274] This drug was developed by Sankyo Co. … [L6142] Pravastatin is made through a fermentation process in which [mevastatin] is first obtained.
Products: Ag-pravastatin, Ag-pravastatin TabletsFinasteride
go.drugbank.com/drugs/DB01216ApprovedInvestigationalIt works in a similar fashion as [dutasteride], which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. … Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone
Products: Ag-finasteride, FINASTERIDE ABCQuetiapine
go.drugbank.com/drugs/DB01224ApprovedInvestigationalIt is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [clozapine] and [olanzapine].[A2189] … [L8546] Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment.
Synonyms: 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanolProducts: Ag-quetiapine, Ag-quetiapine XRAnastrozole
go.drugbank.com/drugs/DB01217ApprovedInvestigationalas compared to earlier estrogen receptor modulators such as [tamoxifen]. … [L8863] Anastrozole is also related to [exemestane], a steroidal AI, but its non-steroidal nature provides stark advantages including a lack of steroid-associated adverse effects such as weight gain and
Products: Ag-anastrozole, Ag-anastrozole TabletsSilodosin
go.drugbank.com/drugs/DB06207ApprovedInvestigationalSilodosin is available as oral capsules with common trade names Rapaflo and Urorec. It is indicated for the symptomatic treatment of benign prostatic hyperplasia in adults. … Silodosin is a selective antagonist of alpha(α)-1 adrenergic receptors that binds to the α<sub>1A</sub> subtype with the highest affinity. α1-adrenergic receptors regulate smooth muscle tone in the bladder
Products: Ag-silodosin, SILODOSIN AL 4 MG HKPAllopurinol
go.drugbank.com/drugs/DB00437ApprovedInvestigationalGout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints [A175942]. … Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and is frequently used in the treatment of chronic gout [A36705
Products: Ag-allopurinol, ALLOPURINOL AL 100Aripiprazole
go.drugbank.com/drugs/DB01238ApprovedInvestigational[L45859] It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. … Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's.
Products: ARIPIPRAZOL AL 5 MG TAB, ARIPIPRAZOL ABZ 5 MG TABBisoprolol
go.drugbank.com/drugs/DB00612ApprovedInvestigationalas [Carvedilol] and [Labetalol]. … [A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs.
Mixtures: CONCOR AM, CONCOR AMInternational brands: SoprolSimvastatin
go.drugbank.com/drugs/DB00641ApprovedInvestigationalas well as the need for surgical revascularization or angioplasty following a heart attack. … Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of _Aspergillus terreus_.
Products: Ag-simvastatin, SIMVASTATINA ABCEplerenone
go.drugbank.com/drugs/DB00700ApprovedInvestigationalEplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative
Products: EPLERENON ABZ 25MG, EPLERENON ABZ 50MG