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Displaying results 91 - 100 of 13096 in total
  1. Drug

    Leucovorin

    go.drugbank.com/drugs/DB00650
    ApprovedInvestigational

    [L56091, L56092] Additionally, it is used in combination with 5-fluorouracil (5-FU) to enhance therapeutic efficacy in the palliative treatment of advanced colorectal cancer and to treat megaloblastic … Leucovorin, also known as folinic acid or citrovorum factor, is a reduced form of folic acid that serves as a vital coenzyme in nucleic acid synthesis.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
  2. Drug

    Filgrastim

    go.drugbank.com/drugs/DB00099
    ApprovedInvestigational

    It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_. … [L40714] Filgrastim was approved in the US in 1991 and there are biosimilars available with similar therapeutic indications.[A245858] Tbo-filgrastim was approved by the FDA on August 29, 2012.

    Products: ZARZIO SOLUTION FOR INJECTION/INFUSION IN A PREFILLED SYRINGE 30MU/0.5ML, Zarzio 48 MU/0.5 ml solution for injection or infusion in pre-filled syringe
  3. Drug

    Varicella zoster vaccine (live/attenuated)

    go.drugbank.com/drugs/DB10318
    ApprovedInvestigational

    Since October 2017, however, it has been replaced as first line therapy by Shingrix ([DB13924]), a more effective and longer lasting vaccine[L1038]. … Clinical trials for Shingrix have shown greater than 90% efficacy in adults aged 50 and older, with 89% efficacy in preventing postherpetic neuralgia in patients 70 years and older and 91% efficacy in

    Mixtures: Priorix - Tetra Pulver in einer Durchstechflasche und Lösungsmittel in einer Fertigspritze zur Herstellung einer InjektionslösungProducts: VARIVAX Pulver und Lösungsmittel zur Herstellung einer Injektionssuspension in einer Fertigspritze, Varilrix Pulver und Lösungsmittel zur Herstellung einer Injektionssuspension in einer Fertigspritze
  4. Drug

    Hepatitis A Vaccine

    go.drugbank.com/drugs/DB10989
    ApprovedInvestigational

    [A199185,L12756] In the US, the approved vaccine is inactivated while live Hepatitis A vaccines are currently available in other countries.[L13392]

    Mixtures: TWINRIX ERİŞKİN IM 1 ML SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, TWINRIX PEDİATRİK IM 0.5 ML SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖRProducts: AVAXIM-SUSPENSION FOR INJ IN A PREFILLED SYRINGE, AVAXIM Injektionssuspension in einer Fertigspritze
  5. Drug

    Clostridium tetani toxoid antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB10583
    ApprovedInvestigational

    The toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium sulfate filtration and precipation. … It is used for active immunization of children 7 years of age or older, and adults, for prevention of tetanus.

    Mixtures: Repevax Injektionssuspension in einer Fertigspritze, Covaxis Injektionssuspension in einer FertigspritzeProducts: TETAVAX single dose, suspension for injection in a prefilled syringe, Tetanus Toxoid Adsorbed Inj
  6. Drug

    Insulin glargine

    go.drugbank.com/drugs/DB00047
    ApprovedInvestigational

    Insulin glargine is also available as the biosimilar, or "follow-on" product, Basaglar in the US and as Abasaglar in the EU. … Insulin is an important treatment in the management of Type 1 Diabetes (T1D), which is caused by an autoimmune reaction that destroys the beta cells of the pancreas, resulting in the body not being able

    Mixtures: SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 50MCG/ML, SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 33MCG/MLCategories: Drugs Used in Diabetes
  7. Target

    Melanoma antigen preferentially expressed in tumors

    go.drugbank.com/bio_entities/BE0010493
    TargetHumans

    In the nucleus, the CRL2(PRAME) complex is recruited to epigenetically and transcriptionally active promoter regions bound by nuclear transcription factor Y (NFY) and probably plays a role in chromstin

    Polypeptides: Melanoma antigen preferentially expressed in tumors
  8. Drug

    Piperacillin

    go.drugbank.com/drugs/DB00319
    ApprovedInvestigational

    It is also used in combination with other antibiotics.

    Mixtures: Zosyn in Galaxy Containers, Zosyn in Galaxy ContainersProducts: Pipracil-pws IV Im 2g/vial, Pipracil-pws IV Im 3g/vial
  9. Drug

    Iohexol

    go.drugbank.com/drugs/DB01362
    ApprovedInvestigational

    Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. … Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.

    Synonyms: N,N'-Bis(2,3-dihydroxypropyl)-5-(N-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamideCategories: Compounds used in a research, industrial, or household setting
  10. Drug

    Haloperidol

    go.drugbank.com/drugs/DB00502
    ApprovedInvestigational

    [A180625] The efficacy of haloperidol was first established in controlled trials in the 1960s.[A180610] … However, these findings contradict the findings from studies in vitro with human liver microsomes and from drug interaction studies in vivo.

    Products: MYUNG IN HALOPERIDOL TABLET 1.5 mg, MYUNG IN HALOPERIDOL INJECTION 5 mg/ml