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Displaying results 91 - 100 of 157601 in total
  1. Drug

    Metoclopramide

    go.drugbank.com/drugs/DB01233
    ApprovedInvestigational

    Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. … [L8417] One unique property of this drug is that it does not increase gastric acid secretion.

    Synonyms: 2-methoxy-5-chloroprocainamide, 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamideMixtures: ESPAVEN MD, PCP 100 Kit
  2. Drug

    Amobarbital

    go.drugbank.com/drugs/DB01351
    ApprovedIllicit

    Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565) … A barbiturate with hypnotic and sedative properties (but not antianxiety).

    Synonyms: 5-ethyl-5-(3-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-ethyl-5-(3-methylbutyl)barbituric acidCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP3A Inducers
  3. Drug

    Oxitriptan

    go.drugbank.com/drugs/DB02959
    ApprovedInvestigationalNutraceuticalWithdrawn

    5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in … Several double-blind placebo-controlled clinical trials have demonstrated the effectiveness of 5-HTP in the treatment of depression, though a lack of high quality studies has been noted.

    Synonyms: L-5-HTP, 5-HTP
  4. Drug

    Pegilodecakin

    go.drugbank.com/drugs/DB15162
    Investigational

    Pegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer).

    Synonyms: INTERLEUKIN 10 (SYNTHETIC HUMAN), DIMER, N-TERMINAL 5-KILODALTON PEGYLATED
  5. Drug

    9-(2-carboxyethyl)-10-methylanthracene endoperoxide

    go.drugbank.com/drugs/DB08332
    Experimental

    Synonyms: 9-(2-carboxyethyl)-10-methylanthracene endoperoxide, [2'-CARBOXYLETHYL]-10-METHYL-ANTHRACENE ENDOPEROXIDE
  6. Drug

    Metronidazole

    go.drugbank.com/drugs/DB00916
    ApprovedInvestigational

    a wide variety of infections. … Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics.

    Synonyms: 1-(2-hydroxy-1-ethyl)-2-methyl-5-nitroimidazole, 2-methyl-5-nitroimidazole-1-ethanolInternational brands: Tricowas B
  7. Drug

    Chlorzoxazone

    go.drugbank.com/drugs/DB00356
    Approved

    A centrally acting central muscle relaxant with sedative properties. … It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)

    Synonyms: 5-chloro-2-benzoxazolol, 5-chloro-2-benzoxazolinoneInternational brands: Remular-S
  8. Drug

    (10R)-10-formyl-5,8,10-trideazafolic acid

    go.drugbank.com/drugs/DB04264
    Experimental

    Synonyms: (10R)-10-formyl-5,8,10-trideazafolic acid
  9. Drug

    Doxycycline

    go.drugbank.com/drugs/DB00254
    ApprovedInvestigationalVet approved

    Doxycycline is a broad-spectrum antibiotic synthetically derived from [oxytetracycline].[L42880] It is a second-generation tetracycline that was first discovered in 1967. … [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.[A251730]

    Mixtures: BenzoDox 30 Kit, BenzoDox 60 KitCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
  10. Drug

    Azacitidine

    go.drugbank.com/drugs/DB00928
    ApprovedInvestigational

    Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity. … As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and inhibiting protein and DNA synthesis.

    Synonyms: 4-amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one, 5 AzacitidineCategories: Heterocyclic Compounds, 1-Ring