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Agalsidase beta
go.drugbank.com/drugs/DB00103ApprovedInvestigationalAgalsidase beta is a recombinant human α-galactosidase A similar to [agalsidase alfa]. … [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009.
Products: ฟาบราไซม์ (5 มก.), REPLAGAL 1 MG/ML IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADETOctreotide
go.drugbank.com/drugs/DB00104ApprovedInvestigationalAcromegaly is a life-threatening disease requiring life-long management. … Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction.
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InhibitorsProducts: SANDOSTATIN VIALES PARA DOSIS MULTIPLE 1 MG/ 5 ML, SANDOSTATIN® LAR® 30 MG MICROESFERAS PARA INYECCIONEnfuvirtide
go.drugbank.com/drugs/DB00109ApprovedInvestigationalThe first agent in the novel class of antiretroviral drugs called HIV fusion inhibitors, enfuvirtide works by inhibiting HIV-1 fusion with CD4 cells. … Enfuvirtide is a 36 amino acid biomimetic peptide that is structurally similar to the HIV proteins that are responsible for the fusion of the virus to cell membranes and subsequent intracellular uptake
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 SubstratesBevacizumab
go.drugbank.com/drugs/DB00112ApprovedInvestigational[A192834,A192888,A192837,A192891,A192894] Bevacizumab is a humanized monoclonal IgG antibody that inhibits angiogenesis by binding and neutralizing VEGF-A. … There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.
Synonyms: 贝伐珠单抗International brands: 安倍斯, 安维汀Technetium Tc-99m arcitumomab
go.drugbank.com/drugs/DB00113ExperimentalThe molecule has a molecular weight of ~54,000 Daltons. … Reduced Fab fragment of the murine IgG1 monoclonal antibody IMMU-4 (also called NP-4) with specificity for carcinoembryonic antigen (CEA) covalently labeled with Technitium 99.
Choline
go.drugbank.com/drugs/DB00122ApprovedInvestigationalNutraceuticalIt is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. … A basic constituent of lecithin that is found in many plants and animal organs.
Mixtures: Formula F L W, Vitamin B Complex W C TabCategories: Vitamin B ComplexSpermine
go.drugbank.com/drugs/DB00127InvestigationalNutraceuticalSpermine is a spermidine-derived biogenic polyamine found as a polycation at all pH values.
Synonyms: N,N'-Bis(3-aminopropyl)-1,4-butanediamineAspartic acid
go.drugbank.com/drugs/DB00128ApprovedInvestigationalNutraceuticalOne of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
Mixtures: AMINOPLASMAL® 10% E, AMINOPLASMAL® 10% ESynonyms: (S)-2-aminosuccinic acid, (S)-2-aminobutanedioic acidOrnithine
go.drugbank.com/drugs/DB00129ApprovedInvestigationalNutraceuticalL-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine.
Mixtures: AMINOPLASMAL-5% E INFUSION, Numeta G 13 % E Emulsion zur InfusionSynonyms: (S)-α,δ-diaminovaleric acid, L-OrnithineL-Glutamine
go.drugbank.com/drugs/DB00130ApprovedInvestigationalNutraceuticalA non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. … An oral formulation of L-glutamine was approved by the FDA in July 2017 for use in sickle cell disease [L892]. This oral formulation is marketed under the tradename Endari by Emmaus Medical.
Synonyms: L-Glutaminsäure-5-amid, L-glutamic acid γ-amideInternational brands: L-Glutamine Power