Search

Displaying results 991 - 1000 of 10000 in total
  1. Drug

    Factor IX Complex (Human)

    go.drugbank.com/drugs/DB11330
    ApprovedInvestigational

    Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. … experiencing acute major bleeding or requiring rapid reversal of therapy.

  2. Drug

    Zuclopenthixol

    go.drugbank.com/drugs/DB01624
    ApprovedInvestigational

    Zuclopenthixol was approved for use in Canada in 2011, but is not approved for use in the United States. … Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent.

  3. Drug

    Zolmitriptan

    go.drugbank.com/drugs/DB00315
    ApprovedInvestigational

    [A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. … Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)<sub>1B/1D/(1F)</sub> receptor agonists used to treat acute migraine.

    Categories: Monoamine Oxidase A SubstratesProducts: ZOLMITRIPTAN AL 5MG, ZOLMITRIPTAN AL 2.5MG
  4. Drug

    Alteplase

    go.drugbank.com/drugs/DB00009
    ApprovedInvestigational

    Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent.[L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. … However, its use for the treatment of acute ischemic stroke (AIS) has increased over the years.

    Mixtures: Activase RT-PA, Lysatec RT - PaSynonyms: t-PA, rt-PA
  5. Drug

    Propanoic acid

    go.drugbank.com/drugs/DB03766
    ApprovedInvestigationalVet approvedWithdrawn

    Sodium propionate is the sodium salt of propionic acid that exists as colorless, transparent crystals or a granular crystalline powder. … Its use as a food additive is also approved in Europe. Sodium propionate is is prepared by neutralizing propionic acid with sodium hydroxide.

  6. Drug

    Venetoclax

    go.drugbank.com/drugs/DB11581
    ApprovedInvestigational

    A new indication was approved in 2018 for the treatment patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), with or without 17p deletion, who have received at least one … Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label].

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  7. Drug

    Sertaconazole

    go.drugbank.com/drugs/DB01153
    Approved

    It is available in topical formulations for the treatment of skin infections such as athlete's foot.

    Categories: Antifungals for Topical Use, Antifungals for Dermatological Use
  8. Drug

    Calcium citrate

    go.drugbank.com/drugs/DB11093
    ApprovedInvestigational

    Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements.

    Mixtures: Natalvirt Ca, Focalgin CACategories: Compounds used in a research, industrial, or household setting
  9. Drug

    Rurioctocog alfa pegol

    go.drugbank.com/drugs/DB16007
    ApprovedInvestigational

    or secondary events like trauma or surgery. … Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor.

    Products: ADYNOVATE 1500IU Powder and Solvent for Solution for Injection, ADYNOVATE 2000IU Powder and Solvent for Solution for Injection
  10. Drug

    Dexmethylphenidate

    go.drugbank.com/drugs/DB06701
    ApprovedInvestigational

    The d-isomer is thought to have greater effect with fewer side effects than the l-isomer or the racemic mixture[A177181]. … It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant[A177193]. It is used for treatment of Attention Deficit Hyperactivity Disorder (ADHD)[Label,A177181].

    Categories: Psychostimulants, Agents Used for ADHD and Nootropics