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Displaying results 991 - 1000 of 10000 in total
  1. Drug

    Iohexol

    go.drugbank.com/drugs/DB01362
    ApprovedInvestigational

    Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. … Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.

    Synonyms: N,N'-Bis(2,3-dihydroxypropyl)-5-(N-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamideCategories: Compounds used in a research, industrial, or household setting
  2. Drug

    Human thrombin

    go.drugbank.com/drugs/DB11571
    ApprovedInvestigational

    This transformation mimics the final coagulation cascade step which involves the clotting mass that adheres to the wound surface and achieves hemostasis and sealing of open tissues. … Furthermore, human thrombin is manufactured by chromatographic purification of prothrombin from cryo-poor plasma followed by activation with calcium chloride [FDA Label].

    Mixtures: EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/mlProducts: THROMBIRAAS1000 UI
  3. Target

    Melanoma antigen preferentially expressed in tumors

    go.drugbank.com/bio_entities/BE0010493
    TargetHumans

    In the nucleus, the CRL2(PRAME) complex is recruited to epigenetically and transcriptionally active promoter regions bound by nuclear transcription factor Y (NFY) and probably plays a role in chromstin … and apoptosis (PubMed:16179254)

    Polypeptides: Melanoma antigen preferentially expressed in tumors
  4. Drug

    Penciclovir

    go.drugbank.com/drugs/DB00299
    Approved

    Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue. … Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections.

    Synonyms: 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanineCategories: Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors
  5. Drug

    Equisetum arvense top

    go.drugbank.com/drugs/DB14349
    ApprovedWithdrawn

    Equisetum arvense top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Products: Silica Aqueous Extract 500mg, BABOR Cleansing Gel and Tonic
  6. Drug

    Alirocumab

    go.drugbank.com/drugs/DB09302
    ApprovedInvestigational

    Alirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of … diet and statin treatment.

    Categories: Amino Acids, Peptides, and ProteinsProducts: PRALUENT®150MG/ML SOLUCIÓN INYECTABLE, PRALUENT SOLUTION FOR INJECTION IN A PRE-FILLED PEN 75MG/ML
  7. Drug

    Dextromethorphan

    go.drugbank.com/drugs/DB00514
    ApprovedInvestigational

    Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. … [A215412] Although similar in structure to other opioids, it has minimal interaction with opioid receptors.[A215412] Dextromethorphan was granted FDA approval before 3 December 1957.

    Mixtures: Acetaminophen 500mg, Dextromethorphan HBr 10mg, Guaifenesin 200mg, Phenylephrine HCl 5mg, BENICAL 10 MG+20MG+2MG/5 ML SURUP, 100 MLCategories: Cough and Cold Preparations, Opium Alkaloids and Derivatives
  8. Drug

    Lipoic acid

    go.drugbank.com/drugs/DB00166
    ApprovedInvestigationalNutraceutical

    A vitamin-like antioxidant.

    Mixtures: Folic-KCategories: Compounds used in a research, industrial, or household setting, Enzymes and Coenzymes
  9. Drug

    Antilymphocyte immunoglobulin (horse)

    go.drugbank.com/drugs/DB09312
    ApprovedInvestigational

    It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. … Induction of T cell apoptosis and resulting T-cell lymphopenia found in vivo is credited for its therapeutic effect in these conditions.

    Categories: Fluids and Secretions, Amino Acids, Peptides, and ProteinsProducts: Atgam Sterile Solution IV 50mg/ml, ATGAM 50MG/ML STERILE SOLUTION (5ML AMP)
  10. Drug

    Aurothioglucose

    go.drugbank.com/drugs/DB09121
    ApprovedWithdrawn

    Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis [A32326]. … and others, which are far more effective.

    Categories: Antiinflammatory and Antirheumatic ProductsProducts: Solganal Inj 50mg/ml