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AGS-16C3F
go.drugbank.com/drugs/DB17551InvestigationalAGS-16C3F is under investigation in clinical trial NCT02639182 (A Study of AGS-16C3F vs. Axitinib in Metastatic Renal Cell Carcinoma).
S65487
go.drugbank.com/drugs/DB17556InvestigationalS65487 a potent and selective BCL-2 inhibitor, and a prodrug of S55746.
Sovleplenib
go.drugbank.com/drugs/DB17557InvestigationalSovleplenib is a novel, investigational, selective small molecule inhibitor for oral administration targeting spleen tyrosine kinase (Syk).
Luveltamab tazevibulin
go.drugbank.com/drugs/DB17563Investigational[A257414] It is under investigation in clinical trial NCT05200364 (A Study of STRO-002, an Anti-folate Receptor Alpha Antibody Drug Conjugate, in Combination With Bevacizumab in Epithelial Ovarian Cancer
Evorpacept
go.drugbank.com/drugs/DB17573InvestigationalEvorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).
Synonyms: A CD47-binding, fusion protein containing a high affinity engineered D1 domain of human signal regulatory protein alpha (SIRPalpha) variant 1 (v1) genetically linked to a modified and inactive Fc domainSS1(dsFv)-PE38
go.drugbank.com/drugs/DB17579InvestigationalSS1(dsFv)-PE38 is a recombinant anti-mesothelin immunotoxin. … SS1(dsFv)-PE38 is under investigation in clinical trial NCT01051934 (A Phase I Trial of SS1 (Dsfv) PE38 With Paclitaxel, Carboplatin, and Bevacizumab in Subjects With Unresectable Non-small Cell Lung Adenocarcinoma
Mezigdomide
go.drugbank.com/drugs/DB17584InvestigationalMezigdomide is under investigation in clinical trial NCT05372354 (A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants
FB-825
go.drugbank.com/drugs/DB17598InvestigationalFB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound IgE (mIgE), causing a depletion of mIgE positive B-cells.
Rexlemestrocel-L
go.drugbank.com/drugs/DB17606InvestigationalRexlemestrocel-L is an investigational human bone marrow-derived allogeneic mesenchymal precursor cell (MPC) product.
Synonyms: Rexlemestrocel-LCDX-6210
go.drugbank.com/drugs/DB17610ExperimentalCDX-6210 is a modified version of a leucine decarboxylase enzyme from _Planctomycetaceae bacterium_.