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Etoposide
go.drugbank.com/drugs/DB00773ApprovedInvestigationalA semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. … Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.
Synonyms: 9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one, 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)International brands: Vepesid KOmidenepag isopropyl
go.drugbank.com/drugs/DB15071ApprovedOmidenepag isopropyl is a topical ocular hypotensive agent used to reduce intraocular pressure (IOP) in patients with glaucoma and ocular hypertension. … The use of an EP2 receptor agonist such as omidenepag represents an alternative in these scenarios. Omidenepag IOP-lowering effect is comparable to the one observed with [latanoprost].
Categories: Heterocyclic Compounds, 1-Ring, Receptors, Prostaglandin E, EP2 Subtype, agonistsSynonyms: isopropyl N-(6-(((4-(1H-pyrazol-1-yl)benzyl)(3-pyridinylsulfonyl)amino)methyl)-2-pyridinyl)glycinateFormoterol
go.drugbank.com/drugs/DB00983ApprovedInvestigationalFormoterol is an inhaled beta<sub>2</sub>-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. … [L11256] It is available as a single-entity product [L10986,L11223] and in several formulations in combination with both inhaled corticosteroids [L10995,L10619] and long-acting muscarinic antagonists.
Synonyms: N-[2-hydroxy-5-(1-hydroxy-2-{[2-(4-methoxyphenyl)-1-methylethyl]amino}ethyl)phenyl]formamide, 2'-hydroxy-5'-(1-hydroxy-2-((p-methoxy-α-methylphenethyl)amino)ethyl)formanilideMixtures: FOSTER 100/6 MCG/DOSE PRESSURISED INHALATION SOLUTION, FORMODUAL N. 200/6UGTick-borne encephalitis vaccine (whole virus, inactivated)
go.drugbank.com/drugs/DB16611ApprovedInvestigational[A237505] TBE often manifests in a biphasic manner, with patients experiencing a flu-like illness followed by a variable asymptomatic period and then a second phase characterized by various neurological … [A237520, L36050] Although TICOVAC was originally based on a master seed virus passaged in mouse brain and then propagated in chicken embryo fibroblast (CEF) cells, since the 1990's, the whole process
Products: FSME-Immun 0,25 ml Junior Injektionssuspension in einer Fertigspritze, FSME-Immun 0,5 ml Erwachsene Injektionssuspension in einer FertigspritzeCyanocobalamin
go.drugbank.com/drugs/DB00115ApprovedInvestigationalNutraceuticalCyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. … This drug was initially approved by the FDA in 1942 [FDA label].
International brands: Cobolin-M, Neuroforte-RMixtures: Multiple Vitamins (Adult) Single Dose, Multiple Vitamins (Pediatric) Single Dose VialDocetaxel
go.drugbank.com/drugs/DB01248ApprovedInvestigational[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and promote to cell death. … Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel].
Synonyms: N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol, N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxelCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProphylaxis of prevention of subtype A viruses contained in the 2015 formula Influenza A Virus Infection
go.drugbank.com/conditions/DBCOND0112776Synonyms: Prophylaxis of prevention of subtype A viruses contained in the 2015 formula Influenza A Virus InfectionGranisetron
go.drugbank.com/drugs/DB00889ApprovedInvestigationalA serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: GRANSET 3 MG/3 ML IV İNFÜZYON ÇÖZELTİSİ, AXIGRAN 1MG/ML KON INJ INFImmunoglobulin A Nephropathy
go.drugbank.com/conditions/DBCOND0063172Drugs: AtrasentanSynonyms: Immunoglobulin A Nephropathy