Search
Tabelecleucel
go.drugbank.com/drugs/DB17072ApprovedInvestigationalTabelecleucel is an innovative therapy that uses Epstein-Barr virus (EBV)-specific allogeneic cytotoxic T cells (CTLs). … Both T-cells and B-cells are obtained from the same donor, and T-cells are grown to increase their numbers.
Upadacitinib
go.drugbank.com/drugs/DB15091ApprovedInvestigationalUpadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic drug (DMARD) used in the treatment of rheumatoid arthritis to slow down disease progression. … [A189168] To reduce dose-related toxicity (as seen with some pan-JAK inhibitors) without significantly affecting efficacy, more selective JAK1 inhibitors, upadacitinib and [filgotinib], were developed.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsCarglumic acid
go.drugbank.com/drugs/DB06775ApprovedInvestigationalThis rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death. … Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase.
Categories: Carbamoyl Phosphate Synthetase 1 Activator, Carbamoyl Phosphate Synthetase 1 ActivatorsSynonyms: (S)-2-ureidopentanedioic acid, N-Carbamyl-L-glutamateBismuth subnitrate
go.drugbank.com/drugs/DB13209ApprovedWithdrawnThe use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA. … Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic
Lithium carbonate
go.drugbank.com/drugs/DB14509ApprovedInvestigationalLithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label].
Mixtures: BIOGROW MINCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexTriclocarban
go.drugbank.com/drugs/DB11155ApprovedTriclocarban, with the chemical formula C13H9Cl3N2O [L2675] is an antibacterial agent that is particularly effective against Gram-positive bacteria such as *Staphylococcus aureus*. … It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products.
Synonyms: 1-(3',4'-dichlorophenyl)-3-(4'-chlorophenyl)urea, N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)ureaProducts: NEXT 1 Anti-bacterial, Next 1 Anti-Bacterial SportVosoritide
go.drugbank.com/drugs/DB11928ApprovedInvestigationalVosoritide is an analog of CNP with proline-glycine on its N-terminus to convey resistance to neutral endopeptidase. … Achondroplasia is an autosomal dominant genetic disease and the most common cause of dwarfism in humans.
Categories: C-type Natriuretic Peptide AnalogDostarlimab
go.drugbank.com/drugs/DB15627ApprovedInvestigationalDostarlimab is an IgG<sub>4</sub> humanized monoclonal antibody targeted against the human programmed death receptor-1 (PD-1). … [A234379] Agents acting on the PD-1 pathway, such as [nivolumab] and [pembrolizumab], facilitate endogenous immune-mediated anti-tumor activity and may therefore be used to treat a wide variety of cancers
Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsSynonyms: Immunoglobulin G4, anti-programmed cell death protein 1 (PDCD1) (humanized clone ABT1 gamma4-chain), disulfide with humanized clone ABT1 kappa-chain, dimerPegulicianine
go.drugbank.com/drugs/DB18731ApprovedInvestigationalPegulicianine itself is a prodrug comprising three main fragments, one of which contains a fluorescence quencher that keeps the parent molecule optically inactive. … [L50537] The _in vivo_ enzymatic cleavage of pegulicianine results in two optically active fragments that emit a fluorescent signal that can be detected using a fluorescence imaging device.
Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingRiboflavin
go.drugbank.com/drugs/DB00140ApprovedInvestigationalNutraceuticalVet approvedNutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms ...
Mixtures: Se-Tan PLUS, VINATAL DHA CAPSULA DE GELATINA BLANDACategories: Vitamin B Complex, Heterocyclic Compounds, 2-Ring