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Bezafibrate
go.drugbank.com/drugs/DB01393ApprovedInvestigationalIt decreases low density lipoproteins and increases high density lipoproteins.
Categories: Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaHexaminolevulinate
go.drugbank.com/drugs/DB06261ApprovedInvestigationalOn May 28, 2010, the U.S. … Hexaminolevulinate is manufactured under the brand Cysview® by Photocure ASA. In Europe, Hexaminolevulinate is marketed under the brand Hexvix®.
Inclisiran
go.drugbank.com/drugs/DB14901ApprovedInvestigational[L39593] It is marketed under the trade name Leqvio. … By binding to PCSK9 messenger RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and plasma concentrations of LDL cholesterol.
Categories: Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaValziflocept
go.drugbank.com/drugs/DB17728InvestigationalSynonyms: Recombinant, soluble, non-glycosylated version of fc gamma receptor iib, Human immunoglobulin gamma fc region receptor ii-b (fc.gamma.rii-b), extracellular n-terminal fragment, produced in escherichia coliTolfenamic acid
go.drugbank.com/drugs/DB09216Approved[A31824] It was discovered by scientists at Medica Pharmaceutical Company in Finland. It is used in the UK as a treatment for migraine under the name of Clotam. … Tolfenamic acid, with the formula N-(2-methyl-3-chlorphenyl)-anthranilic acid, is a nonsteroidal anti-inflammatory agent.
Categories: Analgesics, Non-Narcotic, Non COX-2 selective NSAIDSPralsetinib
go.drugbank.com/drugs/DB15822ApprovedInvestigationalIt is currently marketed under the brand name GAVRETO™ by Blueprint Medicines.[L15986] … [A202055, A219751, L15986] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers, including non-small cell lung cancer.
Infigratinib
go.drugbank.com/drugs/DB11886ApprovedInvestigationalWithdrawnBy inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib suppresses tumour growth. … [A235174] On May 28, 2021, the FDA granted accelerated approval to infigratinib - under the market name Truseltiq - for the treatment of previously treated, unresectable locally advanced or metastatic
Pipotiazine
go.drugbank.com/drugs/DB01621ApprovedInvestigationalWithdrawnIt is used for the maintenance treatment of chronic non-agitated schizophrenic patients. Symptoms of overdose include severe extrapyramidal manifestations, hypotension, lethargy and sedation.
Lornoxicam
go.drugbank.com/drugs/DB06725ApprovedInvestigationalLornoxicam (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties.
Categories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Analgesics, Non-NarcoticIsotretinoin
go.drugbank.com/drugs/DB00982ApprovedInvestigational[L6579] The first isotretinoin-containing product was FDA approved on 7 May 1982.[L6574] … [Label] It was most widely marketed under the brand name Accutane, which has since been discontinued.